Ralph married Annie Cupples 14 Jun 1893, Woodstock, Carleton, New Brunswick, Canada. Annie (daughter of J W Cupples and Elizabeth J Williams) was born 23 Dec 1864, , , New Brunswick, Canada; died 1915, Woodstock, Carleton, New Brunswick, Canada. [Group Sheet]

1. William Ralph Holyoke was born 7 Nov 1898, Woodstock, Carleton, New Brunswick, Canada; died 1930, Atlanta, Fulton, Georgia, United States; was buried , Woodstock Methodist Cemetery, Woodstock, Carleton, New Brunswick, Canada.
2. Frederick Vernon Holyoke was born 27 Nov 1900, Woodstock, Carleton, New Brunswick, Canada; died 5 Oct 1967, Lillooet, , British Columbia, Canada; was buried 8 Oct 1967, Lillooet Cemetery, Lillooet, , British Columbia, Canada.