James married Minnie Clark Oulton 28 Nov 1900, Jolicure, Westmorland, New Brunswick, Canada. Minnie (daughter of John Nelson Oulton and Jerusha Annie Hicks) was born 4 Aug 1876, Jolicure, Westmorland, New Brunswick, Canada; died 24 Oct 1960, Topsfield, , Massachusetts, United States. [Group Sheet]

1. Basil Sylvester Spence was born 18 Mar 1902, Spence Settlement, Westmorland, New Brunswick, Canada; died 2 Oct 1956, Medford, , Massachusetts, United States.
2. Stella Grace Spence was born 7 Jun 1908, Jolicure, Westmorland, New Brunswick, Canada; died 29 Apr 1981, Topsfield, , Massachusetts, United States.